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31 de mayo de 2003

Interim Phase 2 Data Demonstrate Single-Agent Antitumor Activity With ABX-EGF In Advanced Colorectal Cancer

FOR IMMEDIATE RELEASE

CHICAGO, IL, May 31, 2003 -- Abgenix, Inc. (Nasdaq: ABGX) and Amgen, Inc. (Nasdaq:AMGN) today announced interim results from a phase 2 study of ABX-EGF, a fully human monoclonal antibody, demonstrating that ABX-EGF has antitumor activity when administered as a single-agent treatment to patients with advanced colorectal cancer. Results from an interim analysis of a multicenter study, presented at the 39th Annual Meeting of the American Society of Clinical Oncology (ASCO), showed that a majority of patients with measurable metastatic colorectal cancer who over-expressed epidermal growth factor receptor (EGFr) experienced either partial antitumor responses or had stable disease. Results were presented (Abstract #1026) by Neal J. Meropol, MD, Director, Gastrointestinal Cancer Program,

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