Single Company for Amgen Products in New Arrangement

ZUG, Switzerland. (Oct. 4, 2007) -- Amgen, the world´s largest biotechnology company and Dompe Biotec, S.p.A., its co-marketing partner in Italy, announced today that they have agreed to combine their current commercial operations with respect to Amgen products under a single company to be called Amgen-Dompe S.p.A.

Based in Milan, Amgen-Dompe will be organised as an Amgen affiliate and comprise current Amgen and Dompe staff plus current Amgen R&D staff in Italy.

The president of Amgen-Dompe will be Eugenio Aringhieri, who is currently president and chief executive officer of Dompe Biotec, while Marco Renoldi, currently managing director of Amgen Italy, will serve as its managing director. The Board will be made up of four Amgen members and three Dompe members.

"This new arrangement will make our operations in Italy stronger and better organised to achieve sustained long-term growth and continued commitment to excellence in service to patients," said Rolf Hoffmann, senior vice president, Amgen International Commercial Operations.

"With a legacy of 16 years of successful relations, we are embarking on a new era that will combine both companies´ knowledge and expertise to underpin a firm business future for the benefit of our customers and our patients," said Sergio Dompe, president of Dompe Farmaceutici -- Dompe Biotec Holding Company - who will have a seat on the Board of Directors of Amgen International AG, a subsidiary of Amgen International, Inc.

About Amgen

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science´s promise by bringing safe and effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people´s lives. To learn more about our pioneering science and our vital medicines, visit www.amgen.com

About Dompe Biotec

Dompe Biotec, a Dompe eGroup company, was established in 1988 and specializes in the marketing of biotech drugs with a high therapeutic profile in the oncological, haematological and nephrological areas. These drugs have specialized uses and are mostly employed in hospitals.

Dompe Biotec operates with the objective of making a contribution to improving the quality of people´s lives. It does so by providing therapeutic health solutions for the health and wellbeing of mankind, and it is a key partner for the scientific community.

Dompe Biotec´s primary objective is to achieve an excellent positioning in the therapeutical areas in which it operates, with utmost focus on the identification of innovative products which will make a major contribution to patient health.

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CONTACTS: Amgen International Deborah Hibbett (EU media) Office: +41 41 3690 361 Cell: +41 79 800 3529

Dompe Biotec Marta Pagani (media) Office: +39 02 58383302 Cell: +39 338 24 58 674